BayesianPlatformDesignTimeTrend: Simulate and Analyse Bayesian Platform Trial with Time Trend

Simulating the multi-arm multi-stage or platform trial with Bayesian approach using the 'rstan' package, which provides the R interface for the Stan. This package supports fixed ratio and Bayesian adaptive randomization approaches for randomization. Additionally, it allows for the study of time trend problems in platform trials. There are demos available for a multi-arm multi-stage trial with two different null scenarios, as well as for Bayesian trial cutoff screening. The Bayesian adaptive randomisation approaches are described in: Trippa et al. (2012) <doi:10.1200/JCO.2011.39.8420> and Wathen et al. (2017) <doi:10.1177/1740774517692302>. The randomisation algorithm is described in: Zhao W <doi:10.1016/j.cct.2015.06.008>. The analysis methods of time trend effect in platform trial are described in: Saville et al. (2022) <doi:10.1177/17407745221112013> and Bofill Roig et al. (2022) <doi:10.1186/s12874-022-01683-w>.

Version: 1.1.0
Depends: R (≥ 4.0.0), rstan (≥ 2.18.1)
Imports: methods, Rcpp (≥ 0.12.0), RcppParallel (≥ 5.0.1), rstantools (≥ 2.3.0), ggplot2 (≥ 3.4.0), doParallel (≥ 1.0.17), boot (≥ 1.3-28), matrixStats (≥ 0.61.0), stringr (≥ 1.4.0), foreach (≥ 1.5.1), iterators (≥ 1.0.13), reshape (≥ 0.8.8), BiocManager (≥ 1.30.19), lhs (≥ 1.1.6), laGP (≥ 1.5-9)
LinkingTo: BH (≥ 1.66.0), Rcpp (≥ 0.12.0), RcppEigen (≥ 0.3.3.3.0), RcppParallel (≥ 5.0.1), StanHeaders (≥ 2.18.0), rstan (≥ 2.18.1)
Suggests: rmarkdown, knitr
Published: 2023-05-05
Author: Ziyan Wang [aut, cre]
Maintainer: Ziyan Wang <zw7g20 at soton.ac.uk>
License: MIT + file LICENSE
URL: https://github.com/ZXW834/PlatFormDesignTime
NeedsCompilation: yes
SystemRequirements: GNU make, C++17
Materials: README NEWS
CRAN checks: BayesianPlatformDesignTimeTrend results

Documentation:

Reference manual: BayesianPlatformDesignTimeTrend.pdf
Vignettes: MAMS-CutoffScreening-GP-tutorial
MAMS-CutoffScreening-tutorial
MAMS-trial-simulation-tutorial

Downloads:

Package source: BayesianPlatformDesignTimeTrend_1.1.0.tar.gz
Windows binaries: r-devel: BayesianPlatformDesignTimeTrend_1.1.0.zip, r-release: BayesianPlatformDesignTimeTrend_1.1.0.zip, r-oldrel: BayesianPlatformDesignTimeTrend_1.1.0.zip
macOS binaries: r-release (arm64): BayesianPlatformDesignTimeTrend_1.1.0.tgz, r-oldrel (arm64): BayesianPlatformDesignTimeTrend_1.1.0.tgz, r-release (x86_64): BayesianPlatformDesignTimeTrend_1.1.0.tgz, r-oldrel (x86_64): BayesianPlatformDesignTimeTrend_1.1.0.tgz
Old sources: BayesianPlatformDesignTimeTrend archive

Linking:

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